Ipamorelin (10 mg Vial) Dosage Protocol
Research guide for gradual escalation dosing and reconstitution procedures for Ipamorelin, a selective growth hormone secretagogue investigated for GH release stimulation.
Quickstart Highlights
Ipamorelin operates as a synthetic pentapeptide functioning as a selective growth hormone secretagogue through ghrelin mimicry. Its primary benefit lies in specificity for growth hormone release without stimulating ACTH or cortisol elevation, establishing it as one of the safer GH secretagogues with minimal off-target hormonal effects.
- Reconstitute: Add 3.0 mL bacteriostatic water → approximately 3.33 mg/mL concentration
- Weekly dosing schedule: 100 mcg → 150 mcg → 200 mcg → 250 mcg over 12 weeks
- Easy measuring: At 3.33 mg/mL, 1 unit = 0.01 mL ≈ 33 mcg on a U-100 insulin syringe
- Storage: Lyophilized: −20 °C (−4 °F), dry/dark; Reconstituted: 2–8 °C, protected from light
Dosing & Reconstitution Guide
Standard Daily Dosing Protocol
Daily Subcutaneous Protocol (3 mL = ~3.33 mg/mL)
| Week | Daily Dose | Units (per injection) | Volume (mL) |
|---|---|---|---|
| 1–2 | 100 mcg | 3 units | 0.03 mL |
| 3–4 | 150 mcg | 5 units | 0.05 mL |
| 5–8 | 200 mcg | 6 units | 0.06 mL |
| 9–12 | 250 mcg | 8 units | 0.08 mL |
Administration: Administer once daily via subcutaneous injection, preferably 30–60 minutes before bedtime on an empty stomach.
Reconstitution Steps
- Draw 3.0 mL bacteriostatic water using a sterile syringe
- Inject slowly down the vial wall; avoid foaming
- Gently swirl or roll until dissolved (do not shake vigorously)
- Label and refrigerate at 2–8 °C, protected from light
Result: approximately 3.33 mg/mL, where 1 unit = 0.01 mL ≈ 33 mcg on a U-100 insulin syringe
Storage Guidelines
- Lyophilized: −20 °C (−4 °F), dry/dark conditions
- Reconstituted: 2–8 °C (35.6–46.4 °F); do NOT freeze
- Shelf life: 28 days post-reconstitution
Key Administration Notes
- Rotate injection sites to prevent lipohypertrophy
- Gastrointestinal effects common initially; titration minimizes them
- Document weekly dose, date, and injection site
- Use sterile syringes; dispose in sharps container
- Allow vials to reach room temperature before opening
⚠️ Research & Educational Purposes Only
This information is provided for research and educational purposes only. Peptides discussed are intended for laboratory research use only and are not approved for human consumption. Always consult qualified healthcare professionals for medical advice. Individual results may vary. This is not medical advice.