GHRP-6 (5 mg Vial) Dosage Protocol
Reconstitution and dosing guide for the 5 mg GHRP-6 vial — a growth-hormone-releasing peptide and strong appetite stimulant.
Quickstart Highlights
GHRP-6 (Growth Hormone-Releasing Peptide-6) is a synthetic ghrelin-receptor (GHS-R1a) agonist that stimulates a pulse of growth-hormone release from the pituitary. It is known for a pronounced appetite-stimulating effect and is often studied together with a GHRH analog such as CJC-1295. It is administered subcutaneously.
- Composition: 5 mg GHRP-6 per vial
- Reconstitute: Add 2.0 mL bacteriostatic water → 2.5 mg/mL concentration
- Easy measuring: At 2.5 mg/mL, 1 unit (0.01 mL) on a U-100 syringe = 25 mcg
- Storage: Lyophilized: −20 °C (−4 °F); reconstituted: 2–8 °C (35.6–46.4 °F), protected from light, use within 2–4 weeks
Dosing & Reconstitution Guide
Subcutaneous protocol; the standard research dose is around 100 mcg per injection
Subcutaneous Protocol (5 mg vial, 2 mL = 2.5 mg/mL)
| Protocol | Per-dose | Frequency | Units (U-100) |
|---|---|---|---|
| Standard | 100 mcg | 1–3× daily | 4 units (0.04 mL) |
| Higher | 150 mcg | 1–3× daily | 6 units (0.06 mL) |
Administration: Inject subcutaneously on an empty stomach; before bed and/or pre-workout are common. A 5 mg vial provides about 50 doses at 100 mcg.
Reconstitution Steps
- Allow the vial to reach room temperature (15–20 minutes out of cold storage).
- Draw 2.0 mL bacteriostatic water with a sterile syringe.
- Inject slowly down the vial wall to avoid foaming.
- Gently swirl or roll until fully dissolved (do not shake).
- Label with date and concentration; refrigerate at 2–8 °C, protected from light.
Result: 2.5 mg/mL concentration
How This Works
GHRP-6 activates the growth-hormone-secretagogue (ghrelin) receptor on the pituitary, prompting GH release while reducing somatostatin tone. It works through a pathway distinct from GHRH analogs, so the two are commonly combined.
Among the GHRPs, GHRP-6 produces the strongest increase in hunger via ghrelin signaling, which researchers factor into timing and dose.
Key Administration Notes
- Dose on an empty stomach to avoid blunting the GH pulse.
- Expect a strong, transient increase in appetite shortly after dosing.
- Rotate sites; use new sterile insulin syringes and a sharps container.
- Most protocols keep each dose near the ~100 mcg saturation level.
References
Bowers CY, et al. Structure-activity relationships of a synthetic growth hormone-releasing peptide. View Source
Bowers CY, et al. On the in vivo activity of GHRP-6 in humans. View Source
⚠️ Research & Educational Purposes Only
This information is provided for research and educational purposes only. The compounds discussed are intended for laboratory research use only and are not approved for human consumption. Always consult qualified healthcare professionals for medical advice. Individual results may vary. This is not medical advice.